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Sermorelin

Sermorelin is a synthetic peptide corresponding to the first 29 amino acids of endogenous growth hormone–releasing hormone (GHRH 1–29). It is designed to stimulate the anterior pituitary gland to release growth hormone (GH) in a physiologic, pulsatile manner. Due to its shorter active sequence, sermorelin is widely utilized in laboratory settings to study hypothalamic-pituitary signaling and endocrine regulation.

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Research Applications

Third Party Tested by Freedom Diagnostics

Study of hypothalamic-pituitary axis regulation

Investigation of growth hormone (GH) secretion dynamics

Evaluation of IGF-1 production and endocrine feedback loops

Analysis of age-related decline in GH secretion

Technical Information

Technical specifications

Product Specifications

Purity

≥98% (HPLC)

Appearance

White lyophilized powder

Solubility

Water-soluble

Molecular Weight

~3357.9 g/mol

🧊 Storage Requirements

Handling Information

Avoid repeated freeze–thaw cycles

Protect from light and moisture

Lyophilized

-20°C | long-term

Reconstituted

2–8°C

Related Articles

Peer-reviewed research

NCBI Literature Resources

Sermorelin: A better approach to management of adult-onset growth hormone insufficiency

2006 | PMID: 18046908

Richard F Walker

View Source

The role of growth hormone secretagogues in the modern management of body composition in hypogonadal males

Deepankar K. Sinha

View Source

⚠️ Compliance Notice

For laboratory research use only.​ Not intended for human or veterinary use.​ This product has not been evaluated by the U.S. Food and Drug Administration.​

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Support FAQ

Quick answers to common questions

What is Sermorelin and how does it work?​

Sermorelin is a lab-made version of a natural signal in the body that tells the brain to release
growth hormone.
It works by:

  • Stimulating the pituitary gland to release growth hormone
  • Supporting natural hormone production instead of replacing it
  • Potentially helping with body composition, recovery, and metabolism in research settings
How should it be stored?

Store the peptide in the freezer at −20°C for long-term stability.​
After mixing it with liquid, keep it in the refrigerator (2–8°C) and use within about 28 days.​
Avoid repeated freeze-thaw cycles.

Is Sermorelin FDA-approved?

Sermorelin was previously approved for specific medical use (mainly in children with growth
hormone deficiency), but it is not widely used or approved for general treatment today.

What quantity options are available?​

It is usually available in small research vials or kits. Bulk amounts may be available upon
request