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MOTS-c

MOTS-c is a mitochondrial-derived peptide encoded by mitochondrial DNA. It plays a role in
cellular metabolism and stress adaptation.

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Research Applications

Third Party Tested by Freedom Diagnostics

Study of mitochondrial signaling pathways

Evaluation of insulin sensitivity and metabolic regulation

Investigation of aging and exercise physiology

Analysis of AMPK pathway activation

Technical Information

Technical specifications

Product Specifications

Origin

Mitochondrial genome

Function

Metabolic regulator

Target pathways

AMPK, nuclear gene expression

🧊 Storage Requirements

Handling Information

Avoid repeated freeze-thaw cycles

Lyophilized

−20°C

Related Articles

Peer-reviewed research

Metabolites

MOTS-c Functionally Prevents Metabolic Disorders

2023

Yue Gao

View Source

The mitochondrial-derived peptide

MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

2023 • PMID: 25738459

Changhan Lee, Jennifer Zeng

View Source

⚠️ Compliance

Experimental research compound

All the research peptides you need, with the peace of mind and research community at your fingertips.

Support FAQ

Quick answers to common questions

What is MOTS-c and how does it work?​

MOTS-c is a naturally occurring peptide made inside cells, especially in structures called
mitochondria (the “energy centers” of the cell). It works by:

  • Helping the body use energy more efficiently
  • Improving how cells respond to insulin
  • Supporting better control of blood sugar
  • Encouraging the body to burn more fat for energy

Because of this, it is being studied for metabolic health and conditions like obesity and diabetes.

How should it be stored?​

Store the peptide in the freezer at −20°C for long-term stability.​
After mixing it with liquid, keep it in the refrigerator (2–8°C) and use it within about 28 days.​
Avoid repeated freeze-thaw cycles.

Is MOTS-c FDA-approved?​

No. MOTS-c is not FDA-approved for any medical use at this time.

What quantity options are available?​

It is usually available in small research vials or kits. Bulk amounts may be available upon
request