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CJC-1295
CJC-1295 is a synthetic peptide analog of growth hormone–releasing hormone (GHRH). It is
engineered to stimulate the pituitary gland to increase endogenous growth hormone (GH)
secretion through prolonged receptor activation. Modified versions may include a drug affinity
complex (DAC) or similar binding component to extend half-life and improve pharmacokinetic
stability.
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Research Applications
Third Party Tested by Freedom Diagnostics
Investigation of growth hormone pulsatility and regulation
Study of insulin-like growth factor-1 (IGF-1) modulation
Evaluation of endocrine signaling pathways related to GH axis
Analysis of recovery, tissue repair, and metabolic effects in controlled settings
Technical Information
Technical specifications
Product Specifications
Class
GHRH analog (growth hormone secretagogue)
🧊 Storage Requirements
Handling Information
Store frozen before reconstitution
Avoid repeated freeze-thaw cycles
Reconstituted
2–8°C
Potential Benefits
Based on findings from clinical and preclinical research, investigators are exploring several potential effects:
Growth Hormone and IGF-1 Elevation:
Sustained stimulation of GH release leading to increased circulating IGF-1 levels
Body Composition Effects
Observed reductions in fat mass and increases in lean body mass in controlled studies
Recovery and Tissue Repair
Investigated role in muscle recovery and regenerative processes
Sleep and Endocrine Regulation
Potential influence on sleep architecture and circadian GH secretion patterns
Related Articles
Peer-reviewed research
NCBI Literature Resources
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295
2005 | PMID: 16352683
Sam L Teichman
NCBI Literature Resources
Activation of the GH/IGF-1 axis by CJC-1295, a long acting GHRH analog, results in serum protein profile changes in normal adult subjects
2010 | PMID: 19386527
Lucila Sackmann-Sala
⚠️ Compliance Notice
For laboratory research use only. Not intended for human or veterinary use. This product has not been evaluated by the U.S. Food and Drug Administration.
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Support FAQ
Quick answers to common questions
What is CJC-1295, and how does it work?
CJC-1295 is an analog of growth hormone–releasing hormone (GHRH).
It works by:
- Stimulating the pituitary gland to release growth hormone (GH)
- Increasing levels of insulin-like growth factor-1 (IGF-1)
- Supporting protein synthesis and tissue repair processes
- Influencing metabolism, including fat utilization and lean mass regulation
Some versions (e.g., DAC-modified) are designed with an extended half-life, allowing for
prolonged activity in research models
How should it be stored?
Store the peptide in the freezer at −20°C for long-term stability.
After mixing it with liquid, keep it in the refrigerator (2–8°C) and use within about 28 days.
Avoid repeated freeze-thaw cycles.
Is CJC-1295 FDA-approved?
No. CJC-1295 is not approved by the U.S. Food and Drug Administration for any medical use.
It is intended for research purposes only.
What quantity options are available?
CJC-1295 is typically available in small research vials. Custom or bulk quantities may be available.