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Cathelicidin LL-37

Cathelicidin LL-37 is a synthetic cationic antimicrobial peptide derived from the human cathelicidin protein. It consists of a defined amino acid sequence that supports membrane interaction and immune modulation. Supplied as a lyophilized powder for laboratory research.

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Research Applications

Third Party Tested by Freedom Diagnostics

Investigation of antimicrobial activity against bacteria, fungi, and viruses

Analysis of biofilm disruption mechanisms

Evaluation of immune signaling and cytokine modulation

Study of skin barrier function and wound healing

Technical Information

Technical specifications

Product Specifications

Purity

≥95–99% (HPLC)

Appearance

Lyophilized powder

Solubility

Water-soluble

🧊 Storage Requirements

Handling Information

Avoid repeated freeze-thaw cycles

Lyophilized

-20°C

Reconstituted

2–8°C

Related Articles

Peer-reviewed research

NCBI Literature Resources

The human cathelicidin LL-37: a multifunctional peptide involved in infection and inflammation in the lung

2013 • PMID: 15939310

G Sandra Tjabringa, Klaus F Rabe, Pieter S Hiemstra

View Source

NCBI Literature Resources

The Human Cathelicidin Antimicrobial Peptide LL-37 as a Potential Treatment for Polymicrobial Infected Wounds

2013 • PMID: 23840194

Allen J Duplantier, Monique L van Hoek

View Source

⚠️ Compliance Notice

For laboratory research use only. Not approved for clinical application.

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Support FAQ

Quick answers to common questions

What is LL-37 and how does it work?​

LL-37 is part of the body’s natural defense system.​ It works by:

  • Helping kill bacteria, viruses, and other microbes
  • Supporting the immune system’s response to infections
  • Reducing inflammation in certain situations
  • Assisting with wound healing and skin repair

Because of this, it is being studied for infections, immune health, and healing.

How should it be stored?

Store the peptide in the freezer at −20°C for long-term stability.​
After mixing it with liquid, keep it in the refrigerator (2–8°C) and use within about 28 days.​
Avoid repeated freeze-thaw cycles and protect from light.

Is LL-37 FDA-approved?​

No. LL-37 is not FDA-approved for any medical use at this time.

What quantity options are available?

It is usually available in small research vials or kits. Bulk amounts may be available upon
request.